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29 April 2021: Animal Study

miR-1283 Contributes to Endoplasmic Reticulum Stress in the Development of Hypertension Through the Activating Transcription Factor-4 (ATF4)/C/EBP-Homologous Protein (CHOP) Signaling Pathway

Weihao Chen ABC* , Tianhao Liu EF* , Qiuer Liang F* , Xudong Chen BC , Wencong Tao B , Meixia Fang AE* , Ya Xiao AE* , Liguo Chen AEG*

DOI: 10.12659/MSM.930552

Med Sci Monit 2021; 27:e930552

Figure 5 Expression of endoplasmic reticulum stress-related mRNA in human amniotic epithelial cells intervened by miR-1283. (A–G) of activating transcription factor 4 (ATF4), C/EBP-homologous protein (CHOP), BCL-2, BCL-X, BH3-interacting domain death agonist (BID), Bcl-2-like protein 11 (BIM), caspase-3 mRNA expression. Control – control group; mimic – miR-1283 mimic group; inhibitor – miR-1283 inhibitor group; GSK – GSK2656157; mimic control – miR-1283 mimic negative control; inhibitor control – miR-1283 inhibitor negative control group. * P<0.05.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750