Associations Between Cytochrome P450 (CYP) Gene Single-Nucleotide Polymorphisms and Second-to-Fourth Digit Ratio in Chinese University Students

Jing Zhang; Mengyi Yang; Pengfei Luan; Wei Jia; Qiujun Liu; Zhanbing Ma; Jie Dang; Hong Lu; Qian Ma; Yanfeng Wang; Chunlan Mu; Zhenghao Huo

doi:10.12659/MSM.930591

16 March 2021 : Database Analysis

Associations Between Cytochrome P450 (CYP) Gene Single-Nucleotide Polymorphisms and Second-to-Fourth Digit Ratio in Chinese University Students

Jing Zhang^12ABCDEF, Mengyi Yang^1B, Pengfei Luan^1B, Wei Jia^1B, Qiujun Liu^1B, Zhanbing Ma^1A, Jie Dang^1A, Hong Lu^1A, Qian Ma^1B, Yanfeng Wang^1B, Chunlan Mu^1B, Zhenghao Huo^13AG*

DOI: 10.12659/MSM.930591

Med Sci Monit 2021; 27:e930591

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Figure 1 Linkage disequilibrium (LD) map of single-nucleotide polymorphisms (SNPs) in genes CYP17A1 and CYP19A1. A good LD was found among rs1004467, rs2486758, and rs17115149 of CYP17A1(rs1004467 – rs2486758: D’=0.9993, r2=0.1153; rs1004467 – rs17115149: D’=0.6885, r2=0.0202; rs2486758 – rs17115149: D’=0.9964, r2=0.0203); and rs2255192, rs4275794, and rs4646 of CYP19A1(rs2255192 – rs4275794: D’=0.9883, r2=0.9728; rs2255192 – rs4646: D’=0.9992, r2=0.0974; rs4275794 – rs4646: D’=0.9992, r2=0.0978). The haplotypes in the blocks were established based on the LD values.

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Associations Between Cytochrome P450 (CYP) Gene Single-Nucleotide Polymorphisms and Second-to-Fourth Digit Ratio in Chinese University Students

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