16 March 2021: Clinical Research
Associations Between Cytochrome P450 (CYP) Gene Single-Nucleotide Polymorphisms and Second-to-Fourth Digit Ratio in Chinese University Students
Jing Zhang 12ABCDEF , Mengyi Yang 1B , Pengfei Luan 1B , Wei Jia 1B , Qiujun Liu 1B , Zhanbing Ma 1A , Jie Dang 1A , Hong Lu 1A , Qian Ma 1B , Yanfeng Wang 1B , Chunlan Mu 1B , Zhenghao Huo 13AG*DOI: 10.12659/MSM.930591
Med Sci Monit 2021; 27:e930591
Figure 3 Single-nucleotide polymorphism (SNP) interaction graphs analyzed by generalized multifactor dimensionality reduction for second-to-fourth digit ratio (2D: 4D). (A, B) Optimal models as determined by generalized multifactor dimensionality reduction (GMDR) for CYP SNPs (0 = 0 minor allele; 1=1 minor allele; 2=2 minor alleles). The numbers within each small square represent positive scores (left) and negative scores (right). For each square, dark blu cells indicate the high effect on the 2D: 4D, and light blue cells represent the low effect on the 2D: 4D. The test was adjusted for sex.