05 September 2021 : Animal Research
Live Combined B. subtilis and E. faecium Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease
Jie Jiang1BCDE, Jie Xiong1ACEFG*, Jianbo Ni2CDE, Congying Chen2CD, Kezhou Wang3CDOI: 10.12659/MSM.931143
Med Sci Monit 2021; 27:e931143
Figure 1 LCBE prevents abnormal weight, liver weight, and liver index levels, and improves glucose tolerance and insulin resistance in mice fed a high-fat diet (HFD). (A) Body weight; (B) liver index; and (C) blood glucose concentration in the intraperitoneal glucose tolerance test (IPGTT); (D) levels of serum insulin; and (E) determination of HOMA-IR. The data are expressed as means±SD. # P<0.05, ## P<0.01, ### P<0.001 vs Chow, * P<0.05, ** P<0.01, *** P<0.001 vs HFD.