05 September 2021 : Animal Research
Live Combined B. subtilis and E. faecium Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease
Jie Jiang1BCDE, Jie Xiong1ACEFG*, Jianbo Ni2CDE, Congying Chen2CD, Kezhou Wang3CDOI: 10.12659/MSM.931143
Med Sci Monit 2021; 27:e931143
Figure 3 LCBE mitigates systemic inflammation in mice fed a high-fat diet (HFD). The levels of (A, D) interleukin 1β (IL-1β), (B, E) interleukin 6 (IL-6), and (C, F) tumor necrosis factor α (TNF-α) in the serum and liver. (G–H) Protein expression levels of Toll-like receptor 4 (TLR4) and nuclear factor κB (NF-κB) in the liver. The data are expressed as means±SD. * P<0.05, ** P<0.01, *** P<0.001 vs Chow, # P<0.05, ## P<0.01, ### P<0.001 vs HFD.