01 November 2021>: Database Analysis
Identification of Potential Prognostic and Predictive Biomarkers for Immune-Checkpoint Inhibitor Response in Small Cell Lung Cancer
Chanchan Gao E , Xuyu Gu A , Yan Chen C , Min Zhou D , Feng Jiang F , Shiya Zheng G*DOI: 10.12659/MSM.932275
Med Sci Monit 2021; 27:e932275
Figure 6 Validation of the 6 key genes to predict immunotherapeutic response in the CCLE cohort. (A) There was no significant correlation between MCM2 and immune response. (B) Low expression of EZH2 was correlated with favorable response to anti-PD-1 treatment. (C) There was no significant correlation between CDKN2A and immune response (D) Low expression of CENPK was correlated with favorable response to anti-PD-1 treatment. (E) Low expression of CHEK1 was correlated with favorable response to anti-PD-1 treatment. (F) There was no significant correlation between EXOSC2 and immune response. R – response; noR – no response; -L – low-expression group of certain gene; -H – high-expression group of certain gene. (R software (Version 4.0.0, http://www.r-project.org)).