18 October 2021 : Laboratory Research
Salicylate Induced GABAAR Internalization by Dopamine D1-Like Receptors Involving Protein Kinase C (PKC) in Spiral Ganglion Neurons
Jiangyuan Qin1ABCDEF, Tingjia Wei1BCD, Huiying Chen1BCD, Xiaoyu Lin1BC, Danxue Qin1BC, Fangyu Wei1BC, Peiqiang Liu1BC, Wenhua Ye1BC, Jiping Su1ADG*DOI: 10.12659/MSM.933278
Med Sci Monit 2021; 27:e933278
Figure 5 GABA-activated currents recorded in SGNs. (A, B) The suppression of 5 mM SS on GABA-activated currents was reduced by inhibiting D1Rs, then further reduced following co-inhibiting D1Rs and PKC. Data are presented as mean±SD. n=7. * P<0.05 vs GABA group, # P<0.05, vs the SKF group, & P<0.05 vs the SS group, Δ P<0.05, SS+SKF+SCH group vs SS+SKF+SCH+Bis I group, by one-way ANOVA and Tukey test. Pulsefit 8.61 (HEKA, USA) and SPSS 25.0 (USA) were used for the creation of the figures.