03 March 2022 : Clinical Research
Alteration of Serum Metabolites in Women of Reproductive Age with Chronic Constipation
Shuai Liu1ABCEF, Chuanli Yang1ACD, Hongxia Li1BF, Xinshu Bai1B, Tianjiao Hu1B, Xin Xue1B, Jie An1F, Yan Zhang1F, Xiushan Dong1AG*DOI: 10.12659/MSM.934117
Med Sci Monit 2022; 28:e934117
Figure 1 Principal component analysis (PCA) and orthogonal projections to latent structures-discriminant analysis (OPLS-DA) score plots of constipated patients and healthy controls. (A) PCA score plot for patients with constipation vs healthy controls (SIMCA, version 15.0.2, Sartorius Stedim Data Analytics AB, Umea, Sweden). (B) OPLS-DA score plot for patients with constipation vs healthy controls in integrated ion mode (SIMCA). (C) Permutation test of the OPLS-DA model (SIMCA). The slope of R2 is >0 and the Y-intercept of Q2 is <0.05, indicating a valid model.