03 March 2022: Clinical Research
Alteration of Serum Metabolites in Women of Reproductive Age with Chronic Constipation
Shuai Liu ABCEF* , Chuanli Yang ACD* , Hongxia Li BF , Xinshu Bai B , Tianjiao Hu B , Xin Xue B , Jie An F , Yan Zhang F , Xiushan Dong AG*DOI: 10.12659/MSM.934117
Med Sci Monit 2022; 28:e934117
Figure 1 Principal component analysis (PCA) and orthogonal projections to latent structures-discriminant analysis (OPLS-DA) score plots of constipated patients and healthy controls. (A) PCA score plot for patients with constipation vs healthy controls (SIMCA, version 15.0.2, Sartorius Stedim Data Analytics AB, Umea, Sweden). (B) OPLS-DA score plot for patients with constipation vs healthy controls in integrated ion mode (SIMCA). (C) Permutation test of the OPLS-DA model (SIMCA). The slope of R2 is >0 and the Y-intercept of Q2 is <0.05, indicating a valid model.