19 November 2021 : Clinical Research
A Novel Method for the Production of an Autologous Anti-Inflammatory and Anti-Catabolic Product (Cytorich) from Human Blood: A Prospective Treatment for the COVID-19-Induced Cytokine Storm
Irina Brokhman1ABCDEF*, Alyssia M.T. Watkin1BE, Jeffrey C. Bacher1B, Stephen A. Glazer2DE, Anthony M. Galea1ACDEFGDOI: 10.12659/MSM.934365
Med Sci Monit 2021; 27:e934365
Figure 6 Optimal blood incubation condition protocol for interleukin (IL)-1ra and tissue inhibitor of metalloproteinase (TIMP) enrichment did not affect SARS-CoV-2 immunoglobulin (Ig)G concentrations. Samples from immunized patients were analyzed for matrix metalloproteinase (MMP)-9 (A), IL-1β (B), tumor necrosis factor (TNF)-α (C), and anti- SARS-CoV-2 IgG (D) concentrations in control or after 6- or 24-h incubation at 37°C with 4% sodium citrate (SC) (nonsignificant [ns], P>0.01). The figure was created using ImageJ software version 1.53e; Java 1.8.0_172.