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18 March 2022: Clinical Research

Unveiling the Differences in Biological Properties of Dental Pulp Stem Cells from Normal and Inflamed Pulp: A Comprehensive Comparative Study

Shao-Chen Nie 12ABCDEF* , Kun Yang 3ABCD* , Na-Na Luan 12F , Xiao-Li Lian 2B , Xiao-Hua Dai 2C , Su-Xia Liang 12A* , Ying-Bin Yan 24A*

DOI: 10.12659/MSM.934511

Med Sci Monit 2022; 28:e934511

Figure 3 Clonogenic ability, cell proliferation and cell migration of the DPSCs and iDPSCs. (A) The clonogenic potential of DPSCs was significantly higher than that of iDPSCs judged from violet crystal staining. (B) The average colony formation efficiency was calculated from 5 samples. (C) DPSCs showed higher proliferation ability than iDPSCs from days 5 to 8 with CCK-8 test. * P<0.05. (D) The successful migration of DPSCs and iDPSCs showed similar migration potentials with crystal violet staining (magnification, ×20; scale bar, 100 μm); the bar graph represents the average migration rate analyzed from 5 samples. DPSCs – dental pulp stem cells; iDPSCs – inflammatory dental pulp stem cells. (Figure were created using Adobe Photoshop CS3, Adobe Systems Software Ireland, Ltd.).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750