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18 March 2022: Clinical Research

Unveiling the Differences in Biological Properties of Dental Pulp Stem Cells from Normal and Inflamed Pulp: A Comprehensive Comparative Study

Shao-Chen Nie 12ABCDEF* , Kun Yang 3ABCD* , Na-Na Luan 12F , Xiao-Li Lian 2B , Xiao-Hua Dai 2C , Su-Xia Liang 12A* , Ying-Bin Yan 24A*

DOI: 10.12659/MSM.934511

Med Sci Monit 2022; 28:e934511

Figure 4 Osteogenic/dentinogenic differentiation induction analysis. (A) Mineralized nodules were detected after 14 days of induction following alizarin red (AR) staining. “+”, inductive medium; “−”, control medium. Scale bar, 100 μm. (B) The bar chart represents the percentage of area positively stained for AR (mean±standard deviation) analyzed from 5 samples, * P<0.05. (C, D) Several osteogenic/dentinogenic lineage-specific genes were examined by quantitative real-time polymerase chain reaction after 1-week and 2-week induction, * P<0.05. DPSCs – dental pulp stem cells; iDPSCs – inflammatory dental pulp stem cells. (Figure were created using Adobe Photoshop CS3, Adobe Systems Software Ireland, Ltd.).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750