02 December 2021>: Clinical Research
Copy Number Variation Analysis of IL22 and LCE3C in Different Subtypes of Psoriasis in a Chinese Han Population
Caihong Zhu 1234ABCDEF , Wenmin Fei 14BDF , Wenjun Wang 123CD , Lili Tang 123BC , Jinping Gao 1234CF , Fusheng Zhou 1234ACDEFG*DOI: 10.12659/MSM.934927
Med Sci Monit 2021; 27:e934927
Figure 4 Associations of IL22 and LCE3C copy numbers among different severities of psoriasis and healthy controls. (A) The distribution of IL22 CNV was different and inversely correlated with the severity of psoriasis. (B) The distribution of LCE3C CNV was different and inversely correlated with the severity of psoriasis. (C) IL22 copy numbers in mild psoriasis are higher than in severe psoriasis and in healthy controls. (D) LCE3C copy numbers in mild, moderate, and severe psoriasis were lower than in healthy controls. Mild – mild psoriasis; Moderate – moderate psoriasis; Severe – severe psoriasis; HC – healthy control; Blue Bar – the correlation between different CNV group and the BSA score. * P<0.05. (The figure was created by Microsoft Excel 2019 software, Microsoft, USA).