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24 December 2021: Animal Study

Lotus Seedpod Proanthocyanidins Protect Against Light-Induced Retinal Damage via Antioxidative Stress, Anti-Apoptosis, and Neuroprotective Effects

Jianmei Wang 1ABG* , Tao Yu 2B , Liuqing Sheng 1C , Hui Zhang 3D , Fei Chen 1A , Jie Zhu 1F , Mingxing Ding 4AE*

DOI: 10.12659/MSM.935000

Med Sci Monit 2021; 27:e935000

Figure 3 LSPCs improved retinal morphology of light exposure-induced retinal injury rats. (A) The thickness values of outer nuclear layer (ONL) were measured at 1920, 1680, 1440, 1200, 960, 720, 480, and 240 μm superior and inferior to the optic nerve head in control, light-induced retinal damage model, low-, medium-, and high-dose LSPCs groups. Compared with the control group, **** P<0.0001; compared with model group, # P<0.05; ## P<0.01; ### P<0.001; #### P<0.0001. (B) The mean of thickness value of ONL was calculated in each group. **** P<0.0001. GraphPad Prism software (version 8.0.1; Graph Pad; San Diego, CA, USA) was used to create the pictures.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750