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24 December 2021: Animal Study

Lotus Seedpod Proanthocyanidins Protect Against Light-Induced Retinal Damage via Antioxidative Stress, Anti-Apoptosis, and Neuroprotective Effects

Jianmei Wang 1ABG* , Tao Yu 2B , Liuqing Sheng 1C , Hui Zhang 3D , Fei Chen 1A , Jie Zhu 1F , Mingxing Ding 4AE*

DOI: 10.12659/MSM.935000

Med Sci Monit 2021; 27:e935000

Figure 6 Treatment of LSPCs exerted an anti-apoptosis effect in light exposure-induced retina. (A–D) RT-qPCR was utilized for examining the expression of Caspase-3, p53, Bax and Bcl-2 mRNAs in retina from control, light-induced retinal damage model, low-, medium-, and high-dose LSPCs groups. Ns – not significant; ** P<0.01; *** P<0.001; **** P<0.0001. GraphPad Prism software (version 8.0.1; Graph Pad; San Diego, CA, USA) was used to create the pictures.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750