24 December 2021: Animal Study
Lotus Seedpod Proanthocyanidins Protect Against Light-Induced Retinal Damage via Antioxidative Stress, Anti-Apoptosis, and Neuroprotective Effects
Jianmei Wang 1ABG* , Tao Yu 2B , Liuqing Sheng 1C , Hui Zhang 3D , Fei Chen 1A , Jie Zhu 1F , Mingxing Ding 4AE*DOI: 10.12659/MSM.935000
Med Sci Monit 2021; 27:e935000
Figure 7 Treatment of LSPCs alleviated light exposure-induced cell apoptosis in retina. (A) Representative photos of western blotting for pro-Caspase-3, cleaved Caspase-3, p53, Bax as well as Bcl-2 proteins. (B) Quantification of the expressions of pro-Caspase-3, cleaved Caspase-3, p53, Bax, and Bcl-2 as well as Bcl-2/Bax ratio in retina from control, light-induced retinal damage model, low-, medium-, and high-dose LSPCs groups. ** P<0.01; **** P<0.0001. GraphPad Prism software (version 8.0.1; Graph Pad; San Diego, CA, USA) was used to create the pictures.