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12 March 2022: Lab/In Vitro Research

Downregulated Expression of RIPOR3 Correlated with Immune Infiltrates Predicts Poor Prognosis in Oral Tongue Cancer

Kai Zhang 1BCDE , Junlong Da 1F , Xiaoyao Liu 1F , Xinpeng Liu 1F , Jianqun Wang 1F , Han Jin 1D , Ying Li 1D , Bin Zhang 12AG*

DOI: 10.12659/MSM.935055

Med Sci Monit 2022; 28:e935055

Figure 4 Correlation of RIPOR3 with tumor-infiltrating immune cells (TIICs). (A) Violin plot showing the ratio differentiation of 22 kinds of immune cells between oral squamous cell carcinoma of the mobile tongue (OTSCC) samples (n=110), which was filtered by the CIBERSOR algorithm with P<0.05, with low or high RIPOR3 expression relative to the median of the RIPOR3 expression level. (B) Barplot showing the proportion of 22 kinds of TIICs in OTSCC tumor samples. Column names of the plot were sample ID. (C, D) Scatter plot showing the correlation of the stromal cell score and immune cell score with RIPOR3 expression (P< 0.05). (* P<0.05, ** P<0.01, *** P<0.001).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750