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12 March 2022 : Database Analysis  

Downregulated Expression of RIPOR3 Correlated with Immune Infiltrates Predicts Poor Prognosis in Oral Tongue Cancer

Kai Zhang1BCDE, Junlong Da1F, Xiaoyao Liu1F, Xinpeng Liu1F, Jianqun Wang1F, Han Jin1D, Ying Li1D, Bin Zhang12AG*

DOI: 10.12659/MSM.935055

Med Sci Monit 2022; 28:e935055

Figure 6 Correlations between immune cells level and clinicopathological parameters of oral squamous cell carcinoma of the mobile tongue (OTSCC) patients. (A, B) Differential expression of T regs and dendritic cells resting fraction were significantly negatively related to tumor size (P=0.025, P=0.002; T1–2, n=57, T3–4, n=67), while (C) CD4 memory resting T cells were significantly positively correlated with lymph node size (P=0.002, N0=52, N1–3=66). (D) The barplot of KEGG enrichment analysis of most frequently altered neighbor genes in OTSCC with RIPOR3. (E) The dotplot of KEGG enrichment analysis of most frequently altered neighbor genes in OTSCC with RIPOR3. (* P<0.05, ** P<0.01, *** P<0.001).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750