12 March 2022: Lab/In Vitro Research
Downregulated Expression of RIPOR3 Correlated with Immune Infiltrates Predicts Poor Prognosis in Oral Tongue Cancer
Kai Zhang 1BCDE , Junlong Da 1F , Xiaoyao Liu 1F , Xinpeng Liu 1F , Jianqun Wang 1F , Han Jin 1D , Ying Li 1D , Bin Zhang 12AG*DOI: 10.12659/MSM.935055
Med Sci Monit 2022; 28:e935055
Figure 6 Correlations between immune cells level and clinicopathological parameters of oral squamous cell carcinoma of the mobile tongue (OTSCC) patients. (A, B) Differential expression of T regs and dendritic cells resting fraction were significantly negatively related to tumor size (P=0.025, P=0.002; T1–2, n=57, T3–4, n=67), while (C) CD4 memory resting T cells were significantly positively correlated with lymph node size (P=0.002, N0=52, N1–3=66). (D) The barplot of KEGG enrichment analysis of most frequently altered neighbor genes in OTSCC with RIPOR3. (E) The dotplot of KEGG enrichment analysis of most frequently altered neighbor genes in OTSCC with RIPOR3. (* P<0.05, ** P<0.01, *** P<0.001).