28 April 2022 : Review article
Review of the Role of Mesenchymal Stem Cells and Exosomes Derived from Mesenchymal Stem Cells in the Treatment of Orthopedic Disease
Sihang Ren1ACEF, Chenchao Wang1ADEFG*, Shu Guo1AEGDOI: 10.12659/MSM.935937
Med Sci Monit 2022; 28:e935937
Background
Effect of Internal Environment on Exosomes
Potential of Hydrogen
Temperature
Osmotic Pressure
Blood Glucose
Osteogenesis of MSC-Exos in Pathological Environment
Systemic Disease Environment
Orthopedic Disease Environment
Oncologic Disease Environment
Research Significance and Future Prospects
Conclusions
References
Figure 3 The function of mesenchymal stem cell-derived exosomes from the orthopedic or oncologic disease environment. Figure created with BioRender.com.