Bioinformatics Profiling and Experimental Validation of 4 Differentially-Expressed LIM Genes in the Course of Colorectal-Adenoma-Carcinoma

Ying He; Zongfu Pan; Qian Shi; Xilin Zhang; Weiyun Shen; Lixia Huo; Huihui Guo; Chengwu Tang; Yuhang Ling

doi:10.12659/MSM.937081

20 July 2022 : Clinical Research

Bioinformatics Profiling and Experimental Validation of 4 Differentially-Expressed LIM Genes in the Course of Colorectal-Adenoma-Carcinoma

Ying He^12ABEFG, Zongfu Pan^3ACE, Qian Shi^14B, Xilin Zhang^14B, Weiyun Shen^14D, Lixia Huo^14D, Huihui Guo^14D, Chengwu Tang^14FG*, Yuhang Ling^14ACE

DOI: 10.12659/MSM.937081

Med Sci Monit 2022; 28:e937081

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Figure 3 Immunohistochemical validation of the 4 DELGs using mucosa, adenoma, and carcinoma tissues from colorectal cancer patients. (A) Immunohistochemical images. Red and yellow triangles indicate positive expression in the epithelium and mesenchyme, respectively. (B) The expression intensity and positive percentages of the 4 DELGs are represented using H-scores. Data are shown as the mean±SEM (Graphpad, version 8.0.2).

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Bioinformatics Profiling and Experimental Validation of 4 Differentially-Expressed LIM Genes in the Course of Colorectal-Adenoma-Carcinoma

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