28 September 2022: Clinical Research
Factors Predictive of Varicella Zoster Virus Encephalitis/Meningitis: A Single-Center, Retrospective Study
Yanrong Yuan ABCE , Jun Wang BCF , Yan Zhang BC , Huili Liu BC , Yongxing Yan ACDFG*DOI: 10.12659/MSM.938057
Med Sci Monit 2022; 28:e938057
Figure 2 The sensitivity and specificity of CSF ADA in predicting the outcome of VZV encephalitis/meningitis at 3 months after discharge were 77.8% and 81.0%, respectively. The sensitivity and specificity of the time interval from the onset of CNS symptoms to the initiation of antiviral therapy in predicting the outcome of VZV encephalitis/meningitis at 3 months after discharge were 88.9% and 66.7%, respectively. With the combined use of CSF ADA and time interval from the onset of CNS symptoms to the initiation of antiviral therapy, the sensitivity and specificity were 78.8% and 95.4%, respectively, in predicting the outcome of VZV encephalitis/meningitis at 3 months after discharge.