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25 January 2023: Clinical Research

Changes in Heparin-Binding Protein, Procalcitonin, and C-Reactive Protein Within the First 72 Hours Predict 28-Day Mortality in Patients Admitted to the Intensive Care Unit with Septic Shock

Hui Xue ABCDEFG , Feng Yu AFG*

DOI: 10.12659/MSM.938538

Med Sci Monit 2023; 29:e938538

Figure 2 Kinetics of serum HBP, PCT, and CRP in survivors and non-survivors. The upper and lower edges of the box plot represent the 25th and 75th percentiles, respectively. The inner horizontal line represents the median and the whiskers represent the 10th and 90th percentiles. (A) Box plot represents kinetics of serum HBP (HBP0: HBP measurement at the time of admission; HBP1: HBP measurement at the first 72 h of admission). Comparing between groups, P=0.301 at the time of admission and P<0.001 at the first 72 h of admission for heparin-binding protein (HBP). (B) Box plot represents kinetics of serum PCT (PCT0: PCT measurement at the time of admission; PCT1: PCT measurement at the first 72 h of admission). P<0.001 at the time of admission and P<0.001 at the first 72 h of admission for procalcitonin (PCT). (C) Box plot represents kinetics of serum CRP (CRP0: CRP measurement at the time of admission; CRP1: CRP measurement at the first 72 h of admission). P=0.557 at the time of admission and P=0.245 in the first 72 h of admission for CRP. HBP – heparin-binding protein; PCT – procalcitonin; CRP – C-reactive protein. (GraphPad Software, San Diego, CA, USA).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750