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28 March 2023: Database Analysis

A Novel Immune-Related Signature to Predict Prognosis and Immune Infiltration of Cervical Cancer

Yun Lin 1ABCDE , Rendong Zhang 2BCD , Hongchao Pan 1CDG , Yaochen Li 1AEG*

DOI: 10.12659/MSM.938660

Med Sci Monit 2023; 29:e938660

Figure 1 Identification of immune-related genes in cervical cancer.(A) Volcano plot of the differentially expressed genes between cervical cancer and normal tissue. Red points represented the significantly up-regulated genes, while blue points represent the significantly down-regulated genes (adjusted P<0.05). (B) Venn diagram to identify the overlapping genes between differentially expressed genes and immune-related genes. (C) Cross-validation plot for tuning the penalty parameter lambda in the LASSO model. LASSO coefficient profile plot of hub immune-related genes. (D) Forest plot of univariate Cox proportional hazards regression analysis for 10 hub immune-related genes expression and overall survival.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750