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11 March 2023: Database Analysis

Prognostic-Related Biomarkers in Pancreatic Ductal Adenocarcinoma Correlating with Immune Infiltrates Based on Proteomics

Yan-qi Kou 1ACEF* , Yu-ping Yang 1BCE* , Zhao-jie Pan 2E* , Shen-shen Du 1BC* , Wei-nan Yuan 1BC , Kun He 1E , Biao Nie 1A*

DOI: 10.12659/MSM.938785

Med Sci Monit 2023; 29:e938785

Figure 1 Differentially expressed proteins (DEPs) of PDAC network construction and Enrichment analysis of DEPs. (A) Protein–protein interaction (PPI) network of 378 DEPs, with top 21 proteins being shown in red (STRING, version 11.5, https://string-db.org/). (B) The top 21 proteins with the highest degree values were identified using CytoHubba (Cytoscape, version 3.9.1, https://cytoscape.org/). These proteins were ranked in descending degree order from red to orange to yellow. (C) The predicted association rank (from low to high) of the top 30 proteins in the PPI network (R software, version 4.1.2, USA).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750