30 July 2023 : Review article
Enhancing Bone Grafting Outcomes: A Comprehensive Review of Antibacterial Artificial Composite Bone Scaffolds
Yi Liu1AEF, Liuxing He1AFG, Lijia Cheng1AEFG*, Xinsong Li1EF, Min Gao1EF, Qinzhi Li1E, Jingjing Gao1EF, Murugan Ramalingam123FDOI: 10.12659/MSM.939972
Med Sci Monit 2023; 29:e939972
Background
Antibacterial Strategy of Artificial Bone Composites
Progress in Research on Antibiotics-Induced Artificial Bone Scaffolds
Progress in Research on Inorganic Antibacterial Artificial Bone Scaffolds
Ion-Mediated Antibacterial Artificial Bone Scaffolds
Physical Antibacterial Artificial Bone Scaffolds
Nanoparticles-Mediated Antibacterial Artificial Bone Scaffolds
Progress in Research on Natural Antibiotic-Induced Antibacterial Artificial Bone Scaffolds
Animal-Derived Antibacterial Agents
Plant-Derived Antibacterial Agents
Progress in Research on Combined Antibacterial Strategies and Composite Scaffolds
Discussion
Future Directions
Conclusions
References
Figure 1 The therapeutic effectiveness of bone scaffolds is evaluated using different types of bone defects. Before or after the stent is placed in place, bacteria may invade to cause infection, and without antimicrobial treatment, osteomyelitis will develop. Osteomyelitis, which is characterized by bone resorption and reactive bone growth. Originally designed to stop bacterial colonization, infection-resistant scaffolds can also be used to remove existing biofilms and promote defect healing. Created with BioRender.com.