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30 July 2023: Review Articles

Enhancing Bone Grafting Outcomes: A Comprehensive Review of Antibacterial Artificial Composite Bone Scaffolds

Yi Liu 1AEF* , Liuxing He 1AFG* , Lijia Cheng 1AEFG* , Xinsong Li 1EF , Min Gao 1EF , Qinzhi Li 1E , Jingjing Gao 1EF , Murugan Ramalingam 123F

DOI: 10.12659/MSM.939972

Med Sci Monit 2023; 29:e939972

Figure 4 A model showing the cellular mechanism of Ag-NPs exposure to Gram-negative Escherichia coli. Stage A: The disintegration of the cell wall makes the intracellular components leave the cell; Stage B: Ag-NPs entered the cytoplasmic space and began to separate the cytoplasmic fluid from the cell membrane; Stage C: The interaction between Ag-NPs and DNA. Inhibition can lead to ROS production; Stage D: Cell pits appear after exposure; Stage E: Inhibition of normal ribosomal function leads to ROS production protein malformation or inhibition and improper DNA function; Stage F: Production of ROS; G: Interaction with proteins, specific cysteine. Created with BioRender.com.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750