15 June 2023>: Clinical Research
Risk Prediction for Rapidly Progressive Interstitial Lung Disease in Anti-MDA5-Positive Dermatomyositis: The CRAFT Model
Jinqiang Guo 1ABCDEF* , Chunli Mei 1ABCEF* , Qi Yu 2BCD , Anbin Huang 1AEF*DOI: 10.12659/MSM.940251
Med Sci Monit 2023; 29:e940251
Figure 2 The comparison of baseline laboratory examinations between rapidly progressive interstitial lung disease (RP-ILD) and non-RP-ILD patients. The values represented standardized values ranging from 0 to 1 by the min-max normalization. * P<0.05 and ** P<0.001. (Created by RStudio software, version 4.2.0.). MONO – monocytes; PLT – platelet; Ts cells – suppressor T cells; C4 – complement 4; CRP – C-reactive protein; TT – thrombin time; MCHC – mean corpuscular hemoglobin concentration; FIB – fibrinogen; ALB – albumin; RDW-CV – red blood cell distribution width-coefficient of variation; RDW-SD – red blood cell distribution width-standard deviation; PCT – procalcitonin; LYMPH – lymphocytes; NEUT – neutrophils; CAR – C-reactive protein to albumin ratio; IFN-γ – interferon-γ; MCH – mean corpuscular hemoglobin; TNF-α – tumor necrosis factor-α; IL-10 – interleukin-10; IL-6 – interleukin-6; IL-4 – interleukin-4; IL-2 – interleukin-2; Th/Ts, helper T cells/suppressor T cells; NK cells, natural killer cells; Th cells, helper T cells; C3 – complement 3; MCV – mean corpuscular volume; IgM – immunoglobulin M; IgG – immunoglobulin G; IgA – immunoglobulin A; IgE – immunoglobulin E; ESR – erythrocyte sedimentation rate; APTT – activated partial thromboplastin time; INR – international normalized ratio; PT – prothrombin time; LDH – lactate dehydrogenase; HCT – hematocrit; CK – creatine kinase; SLDL – small dense low-density lipoprotein; LDL – low density lipoprotein; HDL – high density lipoprotein; TG – triglyceride; TC – total cholesterol; FBS – fasting blood sugar; AG – anion gap; HGB – hemoglobin; GFR – glomerular filtration rate; UA – uric acid; Cr – creatinine; BUN – blood urea nitrogen; TBA – total bile acid; PA – prothrombin activity; AGR – albumin-to-globulin ratio; GLB – globulin; RBC – red blood cell; TP – total protein; GGT – gamma-glutamyl transpeptidase; ALP – alkaline phosphatase; AST – aspartate transaminase; ALT – alanine transaminase; DBIL – direct bilirubin; TBIL – total bilirubin; PLCR – platelet large cell ratio; PDW – platelet distribution width; MPV – mean platelet volume; WBC – white blood cells. Units: monocytes, 109/L; PLT, 109/L; Ts cells,%; CD3+ T cells,%; C4, g/L; CRP, mg/L; TT, s; MCHC, g/L; FIB, g/L; ALB, g/L; RDW-CV,%; RDW-SD, fl; PCT, ng/mL; lymphocytes, 109/L; neutrophils, 109/L; IFN-γ, pg/mL; MCH, pg; TNF-α, pg/mL; IL-10, pg/mL; IL-6, pg/mL; IL-4, pg/mL; IL-2, pg/mL; Th/Ts,%; NK cells,%; B cells,%; Th cells,%; C3, g/L; MCV, fl; IgM, g/L; IgA, g/L; IgG, g/L; IgE, IU/mL; ESR, mm/h;APTT, s; PT, s; D-Dimer, mg/L; LDH, U/L; HCT,%; CK, U/L; SLDL, mmol/L; LDL, mmol/L; HDL, mmol/L; TG, mmol/L; TC, mmol/L; FBS, mmol/L; AG, mmol/L; Mg2+, mmol/L; Cl–, mmol/L; HGB, g/L; K+, mmol/L; Na+, mmol/L; GFR, ml/min; UA, μmol/L; Cr, μmol/L; BUN, mmol/L; TBA, μmol/L;; AGR,%; GLB, g/L; RBC, 1012/L; TP, g/L; GGT, U/L; ALP, U/L; AST, U/L; ALT, U/L; DBIL, μmol/L; TBIL, μmol/L; PLCR,%; PDW,%; MPV, fl; WBC, 109/L.