Review of the Pathogenesis, Diagnosis, and Management of Osteoradionecrosis of the Femoral Head

Yang Li; Zhongsheng Zhou; Shenghao Xu; Jinlan Jiang; Jianlin Xiao

doi:10.12659/MSM.940264

13 June 2023 : Review article

Review of the Pathogenesis, Diagnosis, and Management of Osteoradionecrosis of the Femoral Head

Yang Li^12EF, Zhongsheng Zhou^12BC, Shenghao Xu^1B, Jinlan Jiang^2A*, Jianlin Xiao^1AE

DOI: 10.12659/MSM.940264

Med Sci Monit 2023; 29:e940264

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Background Hip Anatomy and Biomechanics Epidemiology Pathogenesis Diagnosis and Differential Diagnosis Treatment Future Directions Conclusions References

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Figure 2 Schematic of the damage of radiation on blood vessel. Radiation-induced vascular injury begins with progressive endothelial loss, and followed and partially overlapped by thrombus, wall rapture, and hemorrhage. Long term morphologic changes include endothelial proliferation, basement membrane thickening, adventitial fibrosis, vessel dilatation, and atheroma, which is rich of macrophages. Created with BioRender.com.

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Review of the Pathogenesis, Diagnosis, and Management of Osteoradionecrosis of the Femoral Head

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