15 November 2023 : Database Analysis
Identification of Fibrotic Biomarkers Associated with Macrophages in Diabetic Nephropathy
Rongrong Hou1DE, Lei Gao1C, Junhong Long1B, Jin Cao2F, Tao Yin3A*, Jing Xu1AGDOI: 10.12659/MSM.940847
Med Sci Monit 2023; 29:e940847
Figure 7 In vitro experiments verified the expression of hub genes. (A) Relative mRNA level of MMP2, CASP3, and HIF-1α in MPC5 cells treated with high glucose (HG). (B) Relative mRNA level of MMP2, CASP3, and HIF-1α in THP-1 cells treated with advanced glycation end products (AGEs). (C, D) The secretion of TNF-α and the activity of superoxide dismutase in THP-1 cells. *** Represents P<0.001; ** P<0.01. (GraphPad Prism version 8.0.).