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15 November 2023: Database Analysis

Identification of Fibrotic Biomarkers Associated with Macrophages in Diabetic Nephropathy

Rongrong Hou 1DE , Lei Gao 1C , Junhong Long 1B , Jin Cao 2F , Tao Yin 3A* , Jing Xu 1AG*

DOI: 10.12659/MSM.940847

Med Sci Monit 2023; 29:e940847

Figure 7 In vitro experiments verified the expression of hub genes. (A) Relative mRNA level of MMP2, CASP3, and HIF-1α in MPC5 cells treated with high glucose (HG). (B) Relative mRNA level of MMP2, CASP3, and HIF-1α in THP-1 cells treated with advanced glycation end products (AGEs). (C, D) The secretion of TNF-α and the activity of superoxide dismutase in THP-1 cells. *** Represents P<0.001; ** P<0.01. (GraphPad Prism version 8.0.).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750