14 November 2023 : Clinical Research
Fertility-Sparing Treatment in Gestational Choriocarcinoma: Evaluating Oncological and Obstetrical Outcomes in Young Patients
Szymon Piątek 1ABCDEF*, Natalia Szczęsny 2BE, Iwona Szymusik 3EF, Karolina Karoń2BE, Krzysztof Piątkowski2BE, Ewelina Bornio 2BE, Mariusz Bidziński 1EF, Mariusz Gujski 4EDOI: 10.12659/MSM.942078
Med Sci Monit 2023; 29:e942078
Figure 3 Treatment results and obstetrical outcomes in patients with gestational choriocarcinoma according to International Federation of Gynecology and Obstetrics (FIGO) score and FIGO stage. Response to treatment was assessed according to beta-human chorionic gonadotropin (beta-hCG) serum measurement. Complete response (CR) and progression were considered if beta-hCG dropped to a normal range and increased (or reached plateau), respectively. Patients with progression to first-line chemotherapy underwent salvage treatment: * etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine (EMACO) regimen to both patients and hysterectomy in one patient; ** EMACO regimen; *** cisplatin, vincristine, methotrexate, and bleomycin (POMB) regimen and hysterectomy were used in 1 patient, while another patient had rapid progression and died without salvage treatment.