Metabolomic Alterations in Methotrexate Treatment of Moderate-to-Severe Psoriasis

Yi Zhou; Yantao Ding; Mengxing Cui; Yuanjing Zhang; Mengwei Wang; Feiran Zhou; Yi Su; Bo Liang; Fusheng Zhou

doi:10.12659/MSM.943360

08 May 2024 : Clinical Research

Metabolomic Alterations in Methotrexate Treatment of Moderate-to-Severe Psoriasis

Yi Zhou^123ACDE, Yantao Ding^123BCDE, Mengxing Cui^4F, Yuanjing Zhang^123BCD, Mengwei Wang^32B, Feiran Zhou^5F, Yi Su^6F, Bo Liang^123ACDG*, Fusheng Zhou^123ACD

DOI: 10.12659/MSM.943360

Med Sci Monit 2024; 30:e943360

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Figure 2 Lipid metabolites correlated with the age of onset in patients with psoriasis(A, B) The distribution of Pearson correlation coefficients for diglyceride (DG) metabolites in cohorts 1 and 2. Each dot represents a DG component. The component with correlation coefficient >0.3 or <−0.3, and correlation P value <0.05 are marked. (C) The change in the level of DG (16: 1/18: 1) and DG (18: 1/18: 1) with the age of onset in cohorts 1. (D) The change in the level of (16: 1/18: 1) and DG (18: 1/18: 1) with the age of onset in cohorts 2. (Figures were generated by R with ggplot2_3.4.2.).

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Metabolomic Alterations in Methotrexate Treatment of Moderate-to-Severe Psoriasis

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