26 April 2024 : Laboratory Research
The Role of Copper-Induced M2 Macrophage Polarization in Protecting Cartilage Matrix in Osteoarthritis
Dawei Geng12BCE, Rongcai Lin1BCD, Peiran Wei1ABF, Cheng Tang1CDF, Yan Xu1BCDF, Liming Wang1AF*DOI: 10.12659/MSM.943738
Med Sci Monit 2024; 30:e943738
Figure 3 The expression of cytokines and surface markers in macrophages incubated with BGC and Cu-BGC. The expression of proinflammatory cytokines, IL-1β (A), IL-6 (B) and anti-inflammatory cytokine, IL-4 (C) of macrophages at day 3. The expression of M1 phenotype surface markers, CD86 (D), CCR7 (E), and M2 phenotype surface marker, Arg-1 (F) of macrophages at day 3. The relative gene amount of the CTR group was set as 1. * p<0.05, ** p<0.01, *** p<0.001, n=3.