26 April 2024 : Laboratory Research
The Role of Copper-Induced M2 Macrophage Polarization in Protecting Cartilage Matrix in Osteoarthritis
Dawei Geng12BCE, Rongcai Lin1BCD, Peiran Wei1ABF, Cheng Tang1CDF, Yan Xu1BCDF, Liming Wang1AF*DOI: 10.12659/MSM.943738
Med Sci Monit 2024; 30:e943738
Figure 7 The degradation metabolism of chondrocytes. The expression of MMP3 (A), MMP13 (B) and Adamts5 (C) were co-cultured with 10 ng/ml IL-1β and Cu-BGC for 1 day. The expression of MMP3 (D), MMP13 (E) and Adamts5 (F) were co-cultured with 10 ng/ml IL-1β and Cu2+ ions for 1 day. The relative gene amount of CTR group was set as 1. * p<0.05, ** p<0.01, *** p<0.001, n=3.