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14 May 2024 : Clinical Research  

Correlation between Thalamocortical Tract and Default Mode Network with Consciousness Levels in Hypoxic-Ischemic Brain Injury Patients: A Comparative Study Using the Coma Recovery Scale-Revised

Sung Ho Jang ORCID logo1ABDE, Sang Seok Yeo2ABDE, Min Jye Cho1ACDE, William K. Chung ORCID logo3ABCE*

DOI: 10.12659/MSM.943802

Med Sci Monit 2024; 30:e943802

Figure 1 Diffusion tensor tractography results for representative patients in the disorders of consciousness (DOC) group [patient 1: 43-year-old female with Coma Recovery Scale-Revised (CRS-R) score 8, patient 2: 58-year-old female with CRS-R score 15], one representative patient from the non-DOC group (53-year-old male with CRS-R score 23), and one normal control subject (45-year-old male). (A) T2-weighted brain magnetic resonance images acquired at the time of diffusion tensor imaging scanning. (B) Diffusion tensor tractography results of the thalamocortical tract (TCT) and default mode network (DMN) created using the Oxford Centre for Functional Magnetic Resonance Imaging of Brain (FMRIB) Software Library (FSL, version 5.0.1, Oxford). There is a greater tract volume and integrity of the TCT and the DMN in the non-DOC patient compared to both DOC patients. Furthermore, the tract volume and integrity of the TCT and the DMN (red arrows) in patient 1 are lower than those of patient 2.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750