Targeting the Gut-Kidney Axis in Diarrhea with Kidney-Yang Deficiency Syndrome: The Role of Sishen Pills in Regulating TMAO-Mediated Inflammatory Response

Shiqin Xie; Leyao Fang; Na Deng; Junxi Shen; Zhoujin Tan; Xinxin Peng

doi:10.12659/MSM.944185

20 June 2024 : Animal Research

Targeting the Gut-Kidney Axis in Diarrhea with Kidney-Yang Deficiency Syndrome: The Role of Sishen Pills in Regulating TMAO-Mediated Inflammatory Response

Shiqin Xie^1BCDEF, Leyao Fang^1BCF, Na Deng^1BCD, Junxi Shen^1BC, Zhoujin Tan^1AG*, Xinxin Peng^2AF

DOI: 10.12659/MSM.944185

Med Sci Monit 2024; 30:e944185

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Figure 1 Screening and PPI analysis of “SSP-diarrhea-common targets”. (A) Venn diagram of active compounds of SSPs and diarrhea-related gene targets; (B) PPI interaction network; (C) core targets of PPI interactions. Personal Gene Cloud (https://www.genescloud.cn/login) was used to create Figure A and Cytoscape 3.9.1 was used to create Figure B, C.

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Targeting the Gut-Kidney Axis in Diarrhea with Kidney-Yang Deficiency Syndrome: The Role of Sishen Pills in Regulating TMAO-Mediated Inflammatory Response

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