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20 June 2024 : Animal Research  

Targeting the Gut-Kidney Axis in Diarrhea with Kidney-Yang Deficiency Syndrome: The Role of Sishen Pills in Regulating TMAO-Mediated Inflammatory Response

Shiqin Xie1BCDEF, Leyao Fang1BCF, Na Deng1BCD, Junxi Shen1BC, Zhoujin Tan1AG*, Xinxin Peng2AF

DOI: 10.12659/MSM.944185

Med Sci Monit 2024; 30:e944185

Figure 7 Effects of SSP decoction intervention on renal fibrosis and the intestinal barrier. (A) Renal fibrosis (Masson staining, ×200), quantification of renal fibrosis area (Masson semiquantitative analysis); (B) Expression of Occludin protein in intestinal tissue (immunohistochemistry, ×100, ×400), mean optical density of Occludin; (C) Expression of ZO-1 protein in intestinal tissue (immunohistochemistry, ×100, ×400), mean optical density of ZO-1. The values are expressed as the means±standard deviations (n=3 for each group). * P<0.05. CaseViewer 2.4 and GraphPad Prism 9 were used to construct the figures.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750