06 July 2024 : Clinical Research
Identification of RESP18 Gene Mutations Linked to Hereditary Non-Syndromic Cleft Lip and Palate in a Southern Chinese Family
Xiaoping Zhong12ACEG, Xiaosha Han12BCD, Qihu Xie12BCD, Wanxian Chen12BCD, Deyi Geng12EF, Genghong Guo12EF, Xuefen Chen12BCD, Wancong Zhang12A, Jiasheng Chen12DE, Shijie Tang12ACE*DOI: 10.12659/MSM.944294
Med Sci Monit 2024; 30:e944294
Figure 1 Pedigree of the non-syndromic cleft lip with cleft palate (NSCLP) family. II3, II4, and III2: the proband with the phenotype of NSCLP. I1, I2, I3, I4, II1, II2, II5, II6, III1, III3, and III4: members of the pedigree with no NSCLP phenotype. II3, II4, III2, III3, and III4 represent Cleft_1, Cleft_2, Cleft_3, Normal_1, and Normal_2, respectively. The black symbols represent an affected member, and the arrow indicates the proband. Five members participated in the study (Figure 1, black dotted rectangle).