23 May 2024 : Database Analysis
MRTO4 Enhances Glycolysis to Facilitate HCC Progression by Inhibiting ALDOB
Yongyuan Zheng1ABCD, Yansong Huang1CDE, Weibing Li1CD, Hongqiu Cheng1AEG*DOI: 10.12659/MSM.944685
Med Sci Monit 2024; 30:e944685
Figure 7 Knockdown of ALDOB activated Akt and reverses the low expression of MRTO4 on HCC cell function. (A) Protein blot analysis of ALDOB expression in HCC cells. (B) ELISA evaluation of cell lactate production capacity. (C) ELISA evaluation of cell ATP release levels. (D) CCK8 evaluation of HepG2 and MHCC97H vitality. (E) Clone formation experiment evaluating cell integration ability. (F) Transwell assay was used to assay HCC cell invasion ability. (G) Protein imprint analysis of p-Akt and Akt expression in HCC cells. All results are presented as mean±SD (n=3).* P<0.05, ** P<0.01, *** P<0.001.