03 November 2024 : Database Analysis
Impact of Tigecycline on Coagulation in Severe Infections and Effect of Vitamin K1 Intervention: A Retrospective Single-Center Analysis
Haiyan Sun12ABCDEFG, Xianqing Meng3BDE, Xupeng Shao1BCF, Liyun Duan1DF, Kailiang Fan1ACFG*DOI: 10.12659/MSM.944778
Med Sci Monit 2024; 30:e944778
Figure 4 Comparison of coagulation function indicators with prolonged treatment time. Tigecycline-induced coagulopathy occurred from days 5 to 7. Group comparison: The APTT and PT values of the high-dose (H-D) group were significantly higher than those of the normal-dose (N-D) group on day 7, while the fibrinogen level was significantly lower than that of the normal-dose (N-D) group on days 5 to 7. The figure was created using GraphPad Prism version 9.0.0 (GraphPad Software, Inc, La Jolla, CA, USA).