Impact of Tigecycline on Coagulation in Severe Infections and Effect of Vitamin K1 Intervention: A Retrospective Single-Center Analysis

Haiyan Sun; Xianqing Meng; Xupeng Shao; Liyun Duan; Kailiang Fan

doi:10.12659/MSM.944778

03 November 2024 : Database Analysis

Impact of Tigecycline on Coagulation in Severe Infections and Effect of Vitamin K1 Intervention: A Retrospective Single-Center Analysis

Haiyan Sun^12ABCDEFG, Xianqing Meng^3BDE, Xupeng Shao^1BCF, Liyun Duan^1DF, Kailiang Fan^1ACFG*

DOI: 10.12659/MSM.944778

Med Sci Monit 2024; 30:e944778

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Figure 5 Effect of vitamin K1 intervention on coagulation indices. After treatment with vitamin K1, the fibrinogen increased and APTT and PT were shortened in both groups (H-D group, high-dose group; N-D group, normal-dose group), suggesting that coagulation function improved. The figure was created using GraphPad Prism version 9.0.0 (GraphPad Software, Inc, La Jolla, CA, USA).

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Impact of Tigecycline on Coagulation in Severe Infections and Effect of Vitamin K1 Intervention: A Retrospective Single-Center Analysis

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