11 December 2024 : Review article
Impact of Traditional Chinese Medicine Antioxidants on Oxidative Stress and Drug-Induced Liver Injury: A Review
Jing Zhao AEF 1*, He Liang BF 1, Yanrong Li FG 2, Zimeng Xu B 3, Xueqin Li B 3, Lulu Zhao B 3, Mengqian Zhang B 3, Xuehui Duan B 3DOI: 10.12659/MSM.945147
Med Sci Monit 2024; 30:e945147
Figure 3 A hypothetical model for the alleviation of DILI using TCM-derived antioxidants. In this model, the antioxidants from TCM can alleviate the drug-induced oxidative damage in liver tissues via multiple pathways. Sharp and blunt arrows represent positive and negative effects, respectively. For the details, please see the main text. ROS – reactive oxygen species; SOD – superoxide dismutase; GSH – reduced glutathione; TCM – Traditional Chinese Medicine; DILI – drug-induced liver injury.