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15 November 2024 : Clinical Research  

Adipose-Derived Mesenchymal Stem Cells from Arthritis Patients: Differential Modulation of CD4⁺ T Cell Activation and Cytokine Production

Maciej Ołdak1BC, Weronika Kurowska ORCID logo1DE, Magdalena Plebańczyk1BE, Iwona Janicka1B, Anna Radzikowska ORCID logo1CE, Urszula Skalska ORCID logo1AFG, Ewa Kuca-Warnawin ORCID logo1ABCDEF*

DOI: 10.12659/MSM.945273

Med Sci Monit 2024; 30:e945273

Figure 1 Workflow diagram. Hoffa body a) from patients with RA or OA served as the source of ASCs b). ASCs were cultured with cells from the peripheral blood of healthy donors: isolated CD4+ T cells c) or PBMCs d). After the culture period, analyses of cells (CD4+ T cells) and soluble factors in the culture supernatants were performed. RA, rheumatoid arthritis, OA, osteoarthritis, PBMC, peripheral blood mononuclear cells. Figure created using Power Point.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750