15 November 2024 : Clinical Research
Adipose-Derived Mesenchymal Stem Cells from Arthritis Patients: Differential Modulation of CD4⁺ T Cell Activation and Cytokine Production
Maciej Ołdak1BC, Weronika Kurowska
1DE, Magdalena Plebańczyk1BE, Iwona Janicka1B, Anna Radzikowska 1CE, Urszula Skalska 1AFG, Ewa Kuca-Warnawin 1ABCDEF*
DOI: 10.12659/MSM.945273
Med Sci Monit 2024; 30:e945273
Figure 7 Percentage of Tregs. PBMCs were co-cultured with ASCs (A) or ASCsTI (B) obtained from patients with OA (A, B, n=14). The used solutions were: 1-MT, indomethacin, αTGF-β. Results are shown as single values (box plots) with a standard deviation (vertical lines) and median (horizontal line). The p values for comparisons of co-cultures versus control monocultures are as follows: * 0.05>p>0.01; ** 0.01>p>0.001; *** p<0.001; **** p<0.0001. ASCsTI – ASCs pretreated with TI. Figure created using GraphPad Prism software version 7, Boston, MA, USA.