25 September 2024 : Clinical Research
Enhanced Differentiation of Amiodarone-Induced Thyrotoxicosis Types Using Semi-Quantitative 99mTc-MIBI Uptake Analysis: A Pilot Study
Leo Fischer1BDEF, Neva Girotto1DE*, Maja Ilić Tomaš1BDE, Martina Mavrinac 2CD, Andrica Lekić3CD, Dragana Antončić 4BD, Tatjana Bogović Crnčić1ADEDOI: 10.12659/MSM.945444
Med Sci Monit 2024; 30:e945444
Figure 4 Comparison of 99mTc-Methoxy-2-Isobutylisonitrile (MIBI) thyroid uptake target-to-background ratios (TBRs) in amiodarone-induced thyrotoxicosis (AIT-1, AIT-2, AIT-3) and control groups. Using the mediastinal background region (TBR mediastinal), the differences in MIBI uptake between all AIT groups were statistically significant, while the control group had a significantly higher uptake compared to the AIT-2 group (A). Using the supraclavicular background region (TBR supraclavicular), the differences in MIBI uptake between all AIT groups were statistically significant. The control group had a significantly lower MIBI uptake compared to the AIT-1 group and a significantly higher uptake compared to the AIT-2 group (B). Results are presented as median, interquartile ranges and total range. Level of statistical significance: *** P<0.001 (MedCalc Software, version 20.021, Mariakerke, Belgium).