Figure 3 Electrical responses of central nucleus of the inferior colliculus (CNIC) neurons in the control and model groups at different azimuths. The regular spike trials evoked by paired stimuli (50 ms inter-stimulus delay [ISD]) in CNIC neurons in control group are presented in the pattern of leading-lagging: contralateral 45°-contralateral 18° (A). Local zoom of the leading and lagging sounds evoked potentials at contralateral 45°-contralateral 18° and contralateral 18°-contralateral 45° (B). Histograms of 100 responses from 16 channels are presented at contralateral 45°-contralateral 18° in the control and model groups (inducing electrolytic lesions in the DCIC); at contralateral 18°-contralateral 45° in the control and model groups (C). Mean normalized neuronal responses of the CNIC neurons in the model and control groups are shown at contralateral 45°-contralateral 18° and contralateral 18°-contralateral 45° (D). Bold black arrows represent the start of recording, the bold red arrows represent the onset of the sound, and the bold blue arrows represent the offset of the sound. The thin red arrows represent 1 sound stimulus. Green arrows show the lagging sound evoked spike clusters. The dotted line refers to half-maximal ISDs. Data are expressed as the SEM. Control: n=5, model: n=6; ** P<0.01, *** P<0.001.