13 March 2025 : Review article
Developing Mouse Models for Ovarian Tissue Transplantation and Xenotransplantation: A Review
Feng-xia Liu
EFG 1, Zhong Lin EFG 1, Ka-li Huang A 1*
DOI: 10.12659/MSM.946386
Med Sci Monit 2025; 31:e946386
Introduction
Construction of Mouse Models for Ovarian Tissue Transplantation
Mouse Strains
Ovariectomy Prior to Transplantation
Transplantation Site
Evaluation of Mouse Models for Ovarian Tissue Transplantation
Histological Analysis of the Ovarian Graft
Neovascularization Density
Proliferative Activity of Ovarian Granulosa Cells
Hormonal and Estrous Cycle Monitoring After Transplantation
Timing of Measurements
Future Directions
Conclusions
References
Figure 1 Structure of the review of mouse ovarian tissue transplantation models. OTT – ovarian tissue transplantation.