14 May 2025 : Clinical Research
Efficacy of Prolotherapy for Temporomandibular Joint Dysfunction: An Interventional Clinical Study
Khalil Assiri
AG 1, Abdullah Alqarni AF 1, Hussain Almubarak DF 1, Sultan Mohammed Kaleem ABEF 1*, Saeed Alassiri BCE 1, Fawaz Abdul Hamid Baig ABF 2, Ajmal Muhammed BD 1, Mohammad Zahir Kota BF 2, Ali Azhar Dawasaz BE 1, Ali Mosfer Alqahtani CD 1, Hassan Ahmed Assiri CD 1, Saeed Abdullah Arem DF 1, Salma Abubaker Abbas Ali CF 1, Master Luqman Mannakandath DF 1
DOI: 10.12659/MSM.946650
Med Sci Monit 2025; 31:e946650
Figure 5 Relationship between pain, crepitus, tender muscles, and mouth opening before and after prolotherapy. The study revealed improvement in the crepitus and pain status of all 7 subjects by the third month of therapy, and the VAS score of the subjects was 1.85, on average, by the end of the sixth month. Over time, patients returned to baseline FIQ scores, but indicated pain at the time ranging from some relief to most unpleasant at the initial setup appointment with the second injection. VAS – Visual Analog Scale, FIQ – Fibromyalgia Impact Questionnaire.