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06 December 2024 : Animal Research  

Histological Evaluation of the Effects of Intra-Articular Injection of Caffeic Acid on Cartilage Repair in a Rat Knee Microfracture Model

Mustafa Serpi ABCDEF 1*, Müjdat Adaş ABCD 2, Alev Cumbul ABC 3, Murat Çakar CDEF 2, İsmail Demirkale CEF 4

DOI: 10.12659/MSM.946845

Med Sci Monit 2024; 30:e946845

Figure 7 (A) Low-magnification histological image showing a general view of the tissue section. It explains the healing process with newly formed vessels and inflammatory structures coming to the tissue in the treated area. The empty black asterix shows the wound area of the tissue. In this image, the abnormal vascularization and bone structures in the bone tissue under the cartilage tissue are also clearly visible. The black arrows show the newly formed vessels. Information about the general lines of the wound area can be obtained from the histological image. (B) The histological image at low magnification shows general image of the tissue section. It explains the healing process with newly formed vessels and inflammation structures coming to the tissue in the area where the procedure was performed. The empty black star shows the wound area of the tissue. The abnormal vascularization and bone structures in the bone tissue under the cartilage tissue are also clearly visible. The black arrows show the newly formed vessels. Information about the inflammation of the wound area can be obtained from the histological image. In addition, no cartilage formations are shown. (C) Histological image at low magnification shows a general picture of the tissue section. The healing process is complete, and cartilage structures are formed in the treated area. The black arrows show the newly formed vessels. The bone areas in the sub-cartilage bone tissue have a normal histological appearance. (D) The histological image at low magnification shows a general picture of the tissue section. The healing process is complete, and cartilage structures are formed in the treated area. The bone areas in the sub-cartilage bone tissue have a normal histological appearance.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750