26 January 2025 : Clinical Research
Impact of Periodontal Treatment on Early Rheumatoid Arthritis and the Role of Porphyromonas gingivalis Antibody Titers
Yoichiro Nakajima
1ABCDEF, Nahoko Kato-Kogoe 1ABCDEF*, Takako Yasuda2ABC, Rika Urakawa2BC, Tomoka Matsuo1DF, Michi Omori1BDF, Takaaki Ueno1ADEF, Tohru Takeuchi3ADE
DOI: 10.12659/MSM.947146
Med Sci Monit 2025; 31:e947146
Figure 4 Porphyromonas gingivalis antibody titer and DAS28-CRP. (A) Serum antibody titers against Porphyromonas gingivalis at baseline in the low (L), medium (M), and high (H) groups. (B) Baseline DAS28-CRP levels in each group. (C) DAS28-CRP levels 12 months after RA treatment in each group. The red dotted lines indicate the cutoff values of DAS28-CRP, 2.3, 2.7, and 4.1. * P<0.05, compared with Group L (Kruskal-Wallis test followed by Mann-Whitney U test with Bonferroni correction). DAS28-CRP; disease activity score including 28 joints using C-reactive protein. Created using Microsoft Excel 2016 and PowerPoint 2016 (Microsoft, Redmond, WA, USA).