25 June 2025 : Review article
Antitumor Alkaloids in Tibetan Corydalis: Chemical Diversity and Pharmacological Insights
Linguo Cao ABE 1, Lijun Liu C 2, Yanyan Wang D 1, Jiaqing Liu E 1, Zuowu Xi EFG 3*DOI: 10.12659/MSM.947268
Med Sci Monit 2025; 31:e947268
Introduction
Phytochemical Research
Pharmacologically Guided Q-Marker Discovery: From Compound Identification to Mechanistic Elucidation
Chemotaxonomic Profiling: From Species Differentiation to Geo-Authenticity Assessment
Analytical Technology Revolution: From Single-Component Quantification to Multi-Omics Integration
Tradition Meets Innovation: Processing and Compatibility-Driven Q-Marker Modulation
Clinical Applications
Cell Cycle Arrest
Induction of Tumor Cell Apoptosis
Regulation of the MAPK Signaling Pathway
Suppression of Tumor Angiogenesis
Conclusions
Future Directions
References
Figure 3 Antitumor Mechanisms of Alkaloids from Corydalis: Inhibition of Cell Proliferation, Apoptosis Induction, and Angiogenesis Suppression. Figure were created using Adobe Illustrator CC (Version 26.0, Adobe, Inc., USA).