20 June 2025 : Clinical Research
Machine Learning-Driven Discovery of TRIM Genes as Diagnostic Biomarkers for Idiopathic Pulmonary Fibrosis
Xiangfei Huang CEFG 1, Wen Yu BCE 1, Fuzhou Hua E 2, Aiping Wei E 1, Xifeng Wang AE 1*, Shibiao Chen AEG 1DOI: 10.12659/MSM.948510
Med Sci Monit 2025; 31:e948510
Figure 7 Validation of hub genes in external datasets and clinical samples. (A) The expression levels of the hub genes in GSE33566. (B) The expression levels of the hub genes in GSE38958. (C) The representative CT images of healthy controls and IPF patients. (D) The relative mRNA expression of disease-characteristic genes. n=3 in each group. Data are presented as the mean±SD. Statistical significance was determined using a two-tailed t test. * P<0.05, ** P<0.01, *** P<0.001. The figures were created with GraphPad Prism 9.0.